Glucosamine MSM For Knee Pain | Effectiveness, Dosage, And More!

A popular supplement for joint problems is glucosamine MSM. For knee pain, this combination may help relieve the symptoms.

In fact, taking glucosamine in combination with MSM can provide better relief in certain conditions like knee osteoarthritis. At least compared to taking the supplements alone. (1)

Below, you’ll learn all about the benefits of both glucosamine and MSM for knee pain, whether taken in combination or alone. Also, the best dosage of each for maximum effects and other supplements available.

This is what we’ll cover – tap on any of the topics to navigate easier through the article:

• Benefits of glucosamine MSM for knee pain
• Dosage of glucosamine and MSM
• What is MSM?
• Other supplements for knee pain
• FAQs

Benefits of glucosamine and MSM for knee pain

MSM can enhance the effectiveness of glucosamine and other supplements used to treat arthritis.

For example, a study found that combining MSM with glucosamine and chondroitin was more effective in reducing knee pain and stiffness. At least compared to glucosamine chondroitin alone. (1)

Also, glucosamine boosted by MSM promotes the creation and maintenance of healthy joints.

This is because glucosamine can build and repair cartilage, while MSM prevents its breakdown.

Also, both glucosamine and MSM have anti-inflammatory and analgesic benefits for knee pain. (1)

How does MSM help reduce pain?

MSM can reduce inflammation and prevent the breakdown of cartilage – a connective tissue that cushions joints. (2, 3)

This compound can also help manage joint swelling and stiffness. This effect ultimately leads to improved knee joint functions in people with arthritis, for example. (4)

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What about glucosamine?

Glucosamine is a natural substance found in joints. Taking it as a supplement not only can help maintain healthy cartilage – it can also help reduce inflammation. (5)

Its properties for cartilage rebuilding and swelling management make it a particularly beneficial supplement for knee pain relief.

This is regardless of the form – glucosamine hydrochloride or sulfate – or the condition that’s causing the pain – osteoarthritis or rheumatoid arthritis, for example.

Learn more: Our complete guide on glucosamine for knee pain

Dosage of glucosamine sulfate and MSM for knee joint pain relief

Several studies have found that taking 500 mg of glucosamine combined with 500 mg of MSM can help provide relief from knee pain.

For best results, evidence suggests taking these supplements 3 times per day, for at least 12 weeks. (6)

Read more: What’s the best dosage of glucosamine for knee pain?

Wait – what is MSM?

Methylsulfonylmethane, commonly known as MSM, is a natural chemical that contains sulfur. In supplement form, it looks like a colorless, grainy powder.

However, MSM can be naturally obtained through the consumption of foods such as grains, vegetables, fruits, beer, wine, milk, and tea. (7)

In those with knee pain, MSM supplementation in pill form can be a great strategy.

This will ensure they get an adequate dietary intake of this compound.

There’s clinical evidence that supports the use of MSM for health problems. It shows this compound has beneficial effects in (8, 9):

• Joint pain management.
• Keeping healthy bones.
• Inflammatory conditions like arthritis.
• Allergies.
• Autoimmune diseases.
• Cancer chemoprevention.
• Muscle recovery following exercise.

Other supplements for knee pain

Apart from glucosamine and MSM, there are other supplements available that can help manage knee pain. These include:

• Chondroitin.
• Fish oil.
• Vitamins.
• Magnesium.
• Calcium.
• CBD.

However, please remember that supplements are not the best treatment for reducing pain and other knee joint problems.

To feel significant improvement in your knee pain, you need to know the root cause of your symptoms. Going to a physical therapist is the best way to do so.

Further reading: 8 supplements for knee pain backed by evidence

FAQs

Conclusion: Does glucosamine MSM help knee pain?

MSM is useful for relieving pain associated with knee osteoarthritis. Combining MSM with glucosamine not only provides relief from knee pain but also helps improve knee joint stiffness.

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Glucosamine MSM’s role in promoting cartilage regeneration combined with its anti-inflammatory properties makes it superior to other treatments of knee pain such as nonsteroidal anti-inflammatory drugs.

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